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1

Synthesis and evaluation of cardiac glycoside mimics as potential anticancer drugs

Marie Jensen, Steffen Schmidt, Natalya U. Fedosova, Jan Mollenhauer, Henrik H. Jensen

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 790 KB

english, 2011

2

Fluorescent styryl dyes as probes for Na,K-ATPase reaction mechanism: significance of the charge of the hydrophilic moiety of RH dyes

Fedosova, Natalya U., Cornelius, Flemming, Klodos, Irena

Journal:

Year:

1995

Language:

english

File:

PDF, 1.50 MB

english, 1995

3

Solid-State NMR Studies of Adenosine 5′-Triphosphate Freeze-Trapped in the Nucleotide Site of Na,K-ATPase

David A. Middleton, Eleri Hughes, Natalya U. Fedosova, Mikael Esmann

Journal:

Year:

2009

Language:

english

File:

PDF, 444 KB

english, 2009

4

Anion interactions with Na,K-ATPase: simultaneous binding of nitrate and eosin

Mikael Esmann, Natalya U. Fedosova

Journal:

European Biophysics Journal

Year:

2004

Language:

english

File:

PDF, 314 KB

english, 2004

5

Application of a fluorescent cobalamin analogue for analysis of the binding kinetics : A study employing recombinant human transcobalamin and intrinsic factor

Sergey N. Fedosov, Charles B. Grissom, Natalya U. Fedosova, Søren K. Moestrup, Ebba Nexø, Torben E. Petersen

Journal:

Year:

2006

Language:

english

File:

PDF, 481 KB

english, 2006

6

Diversity of the E2P Phosphoforms of Na, K-ATPase

NATALYA U. FEDOSOVA, FLEMMING CORNELIUS, BLISS FORBUSH III, IRENA KLODOS

Journal:

Annals of the New York Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 234 KB

english, 1997

7

Fluorescent Styryl Dyes as Probes for Na,K-ATPase Reaction : Enzyme Source and Fluorescence Response

IRENA KLODOS, NATALYA U. FEDOSOVA, FLEMMING CORNELIUS

Journal:

Annals of the New York Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 137 KB

english, 1997

8

Eosin as a Probe for Conformational Transitions and Nucleotide Binding in Na,K-ATPase

MIKAEL ESMANN, NATALYA U. FEDOSOVA

Journal:

Annals of the New York Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 630 KB

english, 1997

9

Interaction between Substrate Site and Cation Binding Sites in Pi Phosphorylation of Na,K-ATPase

FLEMMING CORNELIUS, NATALYA U. FEDOSOVA, IRENA KLODOS

Journal:

Annals of the New York Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 174 KB

english, 1997

10

Cation Requirement for Nucleotide Binding to Na,K-ATPase

MIKAEL ESMANN, NATALYA U. FEDOSOVA

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 436 KB

2003

11

Molecular design of Mycoplasma hominis Vaa adhesin

Thomas Boesen, Natalya U. Fedosova, Morten Kjeldgaard, Svend Birkelund, Gunna Christiansen

Journal:

Protein Science

Year:

2001

Language:

english

File:

PDF, 256 KB

english, 2001

12

Nucleotide-Binding Kinetics of Na,K-ATPase: Cation Dependence†

Fedosova, Natalya U., Esmann, Mikael

Journal:

Year:

2004

Language:

english

File:

PDF, 107 KB

english, 2004

13

Dynamic lipid–protein stoichiometry on E1 and E2 conformations of the Na+/K+-ATPase

Irene Mangialavori, Mónica R. Montes, Rolando C. Rossi, Natalya U. Fedosova, Jean Paul F.C. Rossi

Journal:

Year:

2011

Language:

english

File:

PDF, 559 KB

english, 2011

14

Stabilization of Na,K–ATPase by ionic interactions

Elfrieda Fodor, Natalya U. Fedosova, Csilla Ferencz, Derek Marsh, Tibor Pali, Mikael Esmann

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2008

Language:

english

File:

PDF, 587 KB

english, 2008

15

Na,K-ATPase activity modulates Src activation: A role for ATP/ADP ratio

Karl M. Weigand, Herman G.P. Swarts, Natalya U. Fedosova, Frans G.M. Russel, Jan B. Koenderink

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2012

Language:

english

File:

PDF, 484 KB

english, 2012

16

Bulk properties of the lipid bilayer are not essential for the thermal stability of Na,K-ATPase from shark rectal gland or pig kidney

Aida S. Hansen, Kristian L. Kraglund, Natalya U. Fedosova, Mikael Esmann

Journal:

Biochemical and Biophysical Research Communications

Year:

2011

Language:

english

File:

PDF, 209 KB

english, 2011

17

Structural insights into the high affinity binding of cardiotonic steroids to the Na+,K+-ATPase

Laure Yatime, Mette Laursen, J. Preben Morth, Mikael Esmann, Poul Nissen, Natalya U. Fedosova

Journal:

Journal of Structural Biology

Year:

2011

Language:

english

File:

PDF, 2.21 MB

english, 2011

18

Protonation-dependent inactivation of Na,K-ATPase by hydrostatic pressure developed at high-speed centrifugation

Mikael Esmann, Natalya U. Fedosova, Arvid B. Maunsbach

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2000

Language:

english

File:

PDF, 739 KB

english, 2000

19

Osmotic Stress and Viscous Retardation of the Na,K-ATPase Ion Pump

Esmann, Mikael, Fedosova, Natalya U., Marsh, Derek

Journal:

Biophysical Journal

Year:

2008

Language:

english

File:

PDF, 373 KB

english, 2008

20

Stabilisation of Na,K-ATPase structure by the cardiotonic steroid ouabain

Miles, Andrew J., Fedosova, Natalya U., Hoffmann, Søren V., Wallace, B.A., Esmann, Mikael

Journal:

Biochemical and Biophysical Research Communications

Year:

2013

Language:

english

File:

PDF, 1.10 MB

english, 2013

21

A Blue Corrinoid from Partial Degradation of Vitamin B 12 in Aqueous Bicarbonate: Spectra, Structure, and Interaction with Proteins of B 12 Transport

Fedosov, Sergey N., Ruetz, Markus, Gruber, Karl, Fedosova, Natalya U., Kräutler, Bernhard

Journal:

Year:

2011

Language:

english

File:

PDF, 2.15 MB

english, 2011

22

Phosphorylation by Protein Kinase C of Serine-23 of the α -1 Subunit of Rat Na+,K+-ATPase Affects its Conformational Equilibrium

Ninel S. Logvinenko, Irina Dulubova, Natalya Fedosova, Stefan H. Larsson, Angus C. Nairn, Mikael Esmann, Paul Greengard and Anita Aperia

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.17 MB

english, 1996

23

Structural analysis of the yeast exosome Rrp6p–Rrp47p complex by small-angle X-ray scattering

Dedic, Emil, Seweryn, Paulina, Jonstrup, Anette Thyssen, Flygaard, Rasmus Koch, Fedosova, Natalya U., Hoffmann, Søren Vrønning, Boesen, Thomas, Brodersen, Ditlev Egeskov

Journal:

Biochemical and Biophysical Research Communications

Year:

2014

Language:

english

File:

PDF, 1.22 MB

english, 2014

24

Mechanisms of Discrimination between Cobalamins and Their Natural Analogues during Their Binding to the Specific B 12 -Transporting Proteins †

Fedosov, Sergey N., Fedosova, Natalya U., Kräutler, Bernhard, Nexø, Ebba, Petersen, Torben E.

Journal:

Year:

2007

Language:

english

File:

PDF, 349 KB

english, 2007

25

E 2 P Phosphoforms of Na,K-ATPase. II. Interaction of Substrate and Cation-Binding Sites in P i Phosphorylation of Na,K-ATPase †

Cornelius, Flemming, Fedosova, Natalya U., Klodos, Irena

Journal:

Year:

1998

Language:

english

File:

PDF, 173 KB

english, 1998

26

Composite Organization of the Cobalamin Binding and Cubilin Recognition Sites of Intrinsic Factor †

Fedosov, Sergey N., Fedosova, Natalya U., Berglund, Lars, Moestrup, Søren K., Nexø, Ebba, Petersen, Torben E.

Journal:

Year:

2005

Language:

english

File:

PDF, 284 KB

english, 2005

27

Urea-Induced Unfolding of Na,K-ATPase As Evaluated by Electron Paramagnetic Resonance Spectroscopy

Babavali, Mohammad, Esmann, Mikael, Fedosova, Natalya U., Marsh, Derek

Journal:

Year:

2009

Language:

english

File:

PDF, 2.21 MB

english, 2009

28

Detection of circulating tumor cells in pancreatic cancer patients with ISET device

Lyadov, Vladimir, Fedosova, Natalya

Journal:

Year:

2014

Language:

english

File:

PDF, 44 KB

english, 2014

29

Nucleotide Binding to Na,K-ATPase: p K Values of the Groups Affecting the High Affinity Site †

Fedosova, Natalya U., Esmann, Mikael

Journal:

Year:

2007

Language:

english

File:

PDF, 101 KB

english, 2007

30

Assembly of the Intrinsic Factor Domains and Oligomerization of the Protein in the Presence of Cobalamin †

Fedosov, Sergey N., Fedosova, Natalya U., Berglund, Lars, Moestrup, Søren K., Nexø, Ebba, Petersen, Torben E.

Journal:

Year:

2004

Language:

english

File:

PDF, 232 KB

english, 2004

31

Rapid Filtration Analysis of Nucleotide Binding to Na,K-ATPase †

Fedosova, Natalya U., Champeil, Philippe, Esmann, Mikael

Journal:

Year:

2003

Language:

english

File:

PDF, 171 KB

english, 2003

32

E 2 P Phosphoforms of Na,K-ATPase. I. Comparison of Phosphointermediates Formed from ATP and P i by Their Reactivity toward Hydroxylamine and Vanadate †

Fedosova, Natalya U., Cornelius, Flemming, Klodos, Irena

Journal:

Year:

1998

Language:

english

File:

PDF, 108 KB

english, 1998

33

Nucleotide Binding to Na,K-ATPase: The Role of Electrostatic Interactions †

Fedosova, Natalya U., Champeil, Philippe, Esmann, Mikael

Journal:

Year:

2002

Language:

english

File:

PDF, 66 KB

english, 2002

34

Crystals of Na+/K+-ATPase with bound cisplatin

Huliciak, Miroslav, Reinhard, Linda, Laursen, Mette, Fedosova, Natalya, Nissen, Poul, Kubala, Martin

Journal:

Biochemical Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.13 MB

english, 2014

35

Na + ,K + -ATPase Isoform Selectivity for Digitalis-Like Compounds Is Determined by Two Amino Acids in the First Extracellular Loop

Weigand, Karl M., Laursen, Mette, Swarts, Herman G. P., Engwerda, Anthonius H. J., Prüfert, Christian, Sandrock, Julia, Nissen, Poul, Fedosova, Natalya U., Russel, Frans G. M., Koenderink, Jan B.

Journal:

Chemical Research in Toxicology

Year:

2014

Language:

english

File:

PDF, 3.67 MB

english, 2014

36

Structures, chemotaxonomic significance, cytotoxic and Na + ,K + -ATPase inhibitory activities of new cardenolides from Asclepias curassavica

Zhang, Rong-Rong, Tian, Hai-Yan, Tan, Ya-Fang, Chung, Tse-Yu, Sun, Xiao-Hui, Xia, Xue, Ye, Wen-Cai, Middleton, David A., Fedosova, Natalya, Esmann, Mikael, Tzen, Jason T. C., Jiang, Ren-Wang

Journal:

Organic & Biomolecular Chemistry

Year:

2014

Language:

english

File:

PDF, 1.95 MB

english, 2014

37

Structures and characterization of digoxin- and bufalin-bound Na + ,K + -ATPase compared with the ouabain-bound complex

Laursen, Mette, Gregersen, Jonas Lindholt, Yatime, Laure, Nissen, Poul, Fedosova, Natalya U.

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.38 MB

english, 2015

38

Na,K-ATPase structure/function relationships probed by the denaturant urea

Esmann, Mikael, Fedosova, Natalya U., Olesen, Claus

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2015

Language:

english

File:

PDF, 3.77 MB

english, 2015

39

Discovery of Tricyclic Clerodane Diterpenes as Sarco/Endoplasmic Reticulum Ca 2+ -ATPase Inhibitors and Structure–Activity Relationships

De Ford, Christian, Calderón, Carlos, Sehgal, Pankaj, Fedosova, Natalya U., Murillo, Renato, Olesen, Claus, Nissen, Poul, Møller, Jesper V., Merfort, Irmgard

Journal:

Journal of Natural Products

Year:

2015

Language:

english

File:

PDF, 5.05 MB

english, 2015

40

Long-range effects of Na + binding in Na,K-ATPase reported by ATP

Middleton, David A., Fedosova, Natalya U., Esmann, Mikael

Journal:

Year:

2015

Language:

english

File:

PDF, 2.13 MB

english, 2015

41

Isolation, crystallization and crystal structure determination of bovine kidney Na + ,K + -ATPase

Gregersen, Jonas Lindholt, Mattle, Daniel, Fedosova, Natalya U., Nissen, Poul, Reinhard, Linda

Journal:

Acta Crystallographica Section F Structural Biology Communications

Year:

2016

Language:

english

File:

PDF, 702 KB

english, 2016

42

Novel stereoselective bufadienolides reveal new insights into the requirements for Na+, K+-ATPase inhibition by cardiotonic steroids

Tang, Hong-Jin, Ruan, Li-Jun, Tian, Hai-Yan, Liang, Guang-Ping, Ye, Wen-Cai, Hughes, Eleri, Esmann, Mikael, Fedosova, Natalya U., Chung, Tse-Yu, Tzen, Jason T. C., Jiang, Ren-Wang, Middleton, David A.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.51 MB

english, 2016

43

Spin-labelled derivatives of cardiotonic steroids as tools for characterization of the extracellular entrance to the Na + ,K + -ATPase binding site

Guo, Jin-Hua, Jiang, Ren-Wang, Andersen, Jacob Lauwring, Esmann, Mikael, Fedosova, Natalya U.

Journal:

Year:

2018

Language:

english

File:

PDF, 645 KB

english, 2018